Thalidomide-O-amido-C6-NH2 hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

沙利度胺-O-酰胺基-C6-NH2 盐酸盐是一种合成的 E3 连接酶配体-接头缀合物，其中包含基于沙利度胺的 cereblon 配体和接头。它可用于PROTAC的合成。

Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. It can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Others

Other Targets

P450

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2376990-31-5

466.92

C21H27ClN4O6

>98% (HPLC)

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Cl.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

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(-20℃)

With Ice Pack

≥ 2 years